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In vivo , most of these neurons undergo polarization during migration eventually leading to a highly polarized neuron with extensive axonal arbors and dendritic trees

ACLS4 is also a point of regulating ferroptosis through signaling pathways (Wu et al., 2019a): E-cadherin acts through the Merlin-Hippo-Yap pathway to control sensitivity to ferroptosis by regulating expression of ACSL4 in response to cell-cell contacts

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The results of the study demonstrated that miR-124-3p sEVs safeguard DA neurons from 6-OHDA-induced damage in both in vitro and in vivo models, ultimately leading to complete motor function recovery in vivo

doi:10.23736/S0391-1977.18.02824-9 Kumar A, Barki S, Raghav V, Chaturvedi A, Kumar K