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Similarly, in acute ischemic stroke patients, there was upregulation of AGE level and concomitant increase in MMP9 and oxidative stress (Jayaraj et al., 2019)

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This exacerbates the accumulation of harmful reactive species, creating the imbalance known as oxidative stress, contributing to the hyperglycemia-induced tissue damage that drives DR pathogenesis (Figure 3)

Younus et al., 2018): Those with early seizures are at higher risk of developing post-traumatic epilepsy (PTE)