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The topical and systemic application of e.g., antioxidants has been used for the treatment of oxidative stress-related ocular surface disease, especially DED [86, 87]

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Bile acid recognition by the Clostridium difficile germinant receptor, CspC, is important for establishing infection

Over-expression of PON1 in mice confers enhanced HDL anti-oxidative capacity, and PON1 itself prevents LDL oxidation in vitro (432)

For example, CEBPA -deficient mice die shortly after birth due to impaired glucose and lipid metabolism, highlighting CEBPA s essential role in these pathways [132]

2026;157(2):e2025075321