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However, oxygen consumption generates free radicals and other reactive oxygen species which, when excessive and not sufficiently counteracted by cellular antioxidant systems, can produce oxidative stress, toxic to cells and molecules, and to which the brain is particularly susceptible 40

Curcumin not only has powerful antioxidant activity, but it has also been shown to induce the biosynthesis of glutathione within cells

Small human studies support the biological plausibility of both approaches, but there are no robust head-to-head clinical trials proving that one produces better health outcomes than the other

Pelkonen MK, Notkola ILK, Laatikainen TK, Koskela HO

doi: 10.1007/s10522-005-3462-x

[DOI] [PubMed] [Google Scholar] 158.Cagen L.M., Fales H.M., Pisano J.J