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Mitochondrial impairment and dysregulation of mitochondrial proteins are present in postmortem brain and spinal cord tissues of ALS patients and SOD1 G93A mice (Carr et al., 2003
M., Kraus, W
It is a small peptide that appears to interact with several cellular pathways simultaneously
Ethanol metabolism by CYP2E1 generates excess reactive oxygen species (ROS) and depletes glutathione (GSH) in hepatocytes
PubMed PMID: 22074294
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