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[DOI] [PubMed] [Google Scholar] 23.Sun X., Shen J., Wang L
Rodgers explaining the importance of participating in clinical trials
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CYP2D6 Metabolism and Pharmacogenomic Variability The liver converts hydrocodone to hydromorphone via CYP2D6 O-demethylation, producing an active metabolite with approximately 30 times higher mu-opioid receptor affinity than the parent compound
[PubMed] [Google Scholar] 32.Huang N.F., Lam A., Fang Q., Sievers R.E., Li S., Lee R.J
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