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Distinguishing its mechanism from conventional growth factor-based repair approaches

The activity of NF-B and the expression of inflammatory cytokines including TNF-, IL-1, interleukin-6 (IL-6), and matrix metallopeptidase9 (MMP9) were upregulated in Nrf2 KO astrocytes and WT astrocytes, but the increase of which was more apparent in Nrf2 KO astrocytes

Schlegel P, Novotny M, Klimova B, et al

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Nevertheless, the pCTV-WS vaccine offered significant protection to all VOCs

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