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Mouse pancreatic cancer cell lines were obtained from Ptf1a Cre+ , Kras +/LSL-G12D , Trp53 +/LSL-R172H mouse tumours collected in PBS with 1% penicillinstreptomycin and then finely minced

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1 H NMR (700 MHz, D 2 O) : 4.82 (q, J = 6.5 Hz, 1H), 4.37 (t, J = 7.1 Hz, 1H), 3.40 (dd, J = 12.1, 7.6 Hz, 1H), 3.19 (dd, J = 12.1, 6.6 Hz, 1H), 1.53 (d, J = 6.5 Hz, 4H)