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As was mentioned earlier, IGF-1 and its cohorts tend to increase oxidative stress

doi: 10.1128/AAC.44.3.640-646.2000 28 BudhaniR

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We observed upregulation of mRNAs encoding myokines, i.e

On the reproductive axis, recent meta-analyses and RCTs suggest modest improvements in ovulation-induction pregnancy rates and androgen milieu, with reductions in LH and total testosterone in some studies (123)
