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Because the [ 13 C 1 ]acetate tracer enters the acetyl-coenzyme A pool and is oxidized to 13 CO 2 in the Krebs cycle, we measured recovery of 13 CO 2 after an infusion of [ 13 C 1 ]acetate (as an index of Krebs cycle function) and found no change with GSH improvement, suggesting that Krebs cycle function was not altered and that the defect must lie before it

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The Circadian Clock Gene Csnk1e Regulates Rapid Eye Movement Sleep Amount, and Nonrapid Eye Movement Sleep Architecture in Mice

Garvey WT, Mechanick JI, Brett EM, et al

Ions Biol