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For instance, with a 5 mg/mL solution, 10 units corresponds to 0.5 mg, whereas with a 10 mg/mL solution, 10 units would be 1 mg

UCHs, ubiquitin C-terminal hydrolases

Under hypoxic conditions, human macrophages inhibit ferritin autophagy by reducing the expression of nuclear receptor coactivator 4 (NCOA4), resulting in increased mitochondrial ferritin expression and decreased intracellular free iron, thus regulating ferroptosis [35]

As observed in cancer cells, injecting this inducer caused an escalation in intracellular iron levels, accompanied by ROS production and GSH depletion, ultimately triggering ferroptosis [134]

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