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For MAPK pathways, KPV inhibits all three subfamilies: ERK1/2 (extracellular signal-regulated kinases) JNK (c-Jun N-terminal kinases) p38 MAPK Phosphorylation of these kinasesrequired for activationdrops markedly in cells exposed to KPV

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The main goal of lumbar epidural steroid injections is to manage chronic pain caused by irritation and inflammation of the spinal nerve roots in your low back (the lumbar region of your spine) due to certain conditions or injuries