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Although O 2 itself is poorly reactive with most biological substrates in aqueous environments [89], it serves as a progenitor for a number of other, more microbicidal ROS and plays a critical role in mediating a wide range of cellular signaling processes

2 Schematic representation of the interactions between natural antioxidants and the reproductive tract

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from diet) reactivates human telomerase reverse transcriptase (hTERT), which might collaborate with genetic factors to drive colon tumorigenesis [95]

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Potential roles of mitochondrial cofactors in the adjuvant mitigation of proinflammatory acute infections, as in the case of sepsis and COVID-19 pneumonia