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People with long-term illnesses such as diabetes, osteoporosis, muscular degeneration, and Lou Gehrigs disease tend to fare better when they supplement their diet with vitamin B12

Trial populations have included a wide age range

To keep the broadened substrate scope, ALOX12/15 can be reactive towards intact PLs which do not require the PLs hydrolysis for peroxidation

In addition, it was demonstrated that folic acid supplementation over a 3 year period in men and postmenopausal women aged from 50 to 70 years reduced the rate of cognitive decline (79)

Dosage 1,200 to 2,400 mg per day split across morning and early afternoon doses

Gallego-Durn, R