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In a study done with 128 Covid Patients, 10 weeks after patients had the virus and had tested negative, they still reported a persisting, debilitating fatigue

Hypotheses include an effect of metformin on the intestinal flora leading to bacterial overgrowth and B12 malabsorption, and an indirect effect of metformin on the enterohepatic circulation of B12

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The hippocampus plays a crucial role in spatial navigation and analyzing search strategies of mice during the MWM task allows to differentiate between hippocampus-dependent allocentric and hippocampus-independent egocentric search strategies 28,29,30

Within the class S4 of hormone and metabolic modulators of the WADA Prohibited List, 39% of the adverse analytical findings (AAF) reported in 2020 resulted from SERMs (tamoxifen and clomiphene) and another 29% from AIs (letrozole, anastrozole, exemestane, and adrostatrienedione) (World Anti-Doping Agency, 2022)