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Cytotoxicity and therapeutic effect of irinotecan combined with selenium nanoparticles

In the field of histone modification, panobinostat, an HDAC inhibitor that belongs to the cinnamic hydroxamic acid class of compounds that inhibits HDAC1, 36 at nanomolar concentrations [133, 134], has exhibited cytotoxic effects by inducing cell cycle arrest and apoptosis in ATC cell lines both in vitro and in vivo [51], but its clinical efficacy remains limited

doi: 10.1007/s11060-024-04934-6

Also included is a method of administering a compound of formula (I) to a subject who has any one or more of the conditions listed herein, such as diabetes mellitus or hypertension

Applying hot or cold compresses can reduce inflammation and pain, offering temporary relief

Sweeney et al., 2018)