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Hippocampal neurons are particularly affected, linking calcium dysregulation to paradoxical memory impairment (97, 98)

The observed plasma increase in adenosine could be due to a decrease in adenosine deaminase activity, inhibition of adenosine kinase, or an increase in 5-nucleotidase, all of which can occur in the presence of oxidative stress [7072]

Environment international , 112 , 287

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Investigating and addressing deficiencies of minerals and other key nutrients is equally important for treating other signs and symptoms of ASD, particularly inflammation and oxidative stress