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Description
Collectively, these studies provide evidence that the L-carnitine system is differentially impacted by APOE genotypes with age and following L-carnitine challenge which could later contribute to AD pathogenesis through bioenergetics deficits, FA toxicity, and cerebrovascular dysfunction in E4s, especially in females
J Cell Sci
Birch EE, Khoury JC, Berseth CL, et al
10.1038/gim.2016.42 Genet
Pharmacological cancer treatment and mitochondrial health It is generally recognised that all oncological treatments affect several aspects of mitochondrial life cycle and function, with varying degrees of impact depending on the cell type
