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A subset of clinical research has also demonstrated that adding B12 (and other B-vitamins) to existing antidepressant regimens can improve response rates compared to antidepressants alone, particularly when baseline B12 was suboptimal

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Phase II trial of BXCL701 and pembrolizumab in patients with metastatic pancreatic ductal adenocarcinoma (EXPEL-PANC)

For example: if you purchase an eligible item for $100 but only have $60 in your account, you can reimburse $60 of your purchase with your tax-free funds (with the remaining $40 paid for as normal)