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The skin is chronically exposed to both endogenous and environmental pro-oxidants leading to the production of ROS.[] ROS leads to lipid peroxidation, which is considered as the hallmark of oxidative stress in body.[] Malondialdehyde (MDA) is considered as the end product of lipid peroxidation and MDA levels is directly proportional to the oxidative stress.[] The most important antioxidants present in human body include superoxide dismutase, glutathione peroxidase, and catalase.[] Glutathione which is considered a master antioxidant can help keep the balance between the oxidant and antioxidant system in the body and prove to be an effective therapy but studies proving its efficacy are limited

Western blot analysis was employed to confirm Nrf2 knockdown at 24 h post-transfection

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Based on thirty years of interviews, this masterful biography is filled with insights into the life and work of this complex, fascinating man.

J Pharmacol Exp Ther 289:361370 Seme MT, Summerfelt P, Neitz J, Eells JT, Henry MM (2001) Differential recovery of retinal function after mitochondrial inhibition by methanol intoxication

Yengi L, Inskip A, Gilford J, Alldersea J, Bailey L, Smith A et al