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While the -2a or isoform of OGG1 was initially presumed to be the main mitochondrial isoform [135], a recent study demonstrated that the endogenous mitochondrial-targeting sequence of the predominant -1a isoform is sufficient to target both the nucleus and mitochondria [151]

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According to the current WHO classification from 2011, lung carcinomas are classified as adenocarcinoma (ADC), squamous cell carcinoma (SCC), small cell lung cancer (SCLC), large cell neuroendocrine carcinoma (LCNEC), non-small cell carcinoma-carcinoid tumor not otherwise specified (NSCC-NOS), etc

The dysfunction of neurons, astrocyte, and other cells exacerbates microglial activation, neuroinflammation, and NeuroHIV [169, 170]

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Liu, F., et al., Intravenous high-dose vitamin C for the treatment of severe COVID-19: study protocol for a multicentre randomised controlled trial