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doi: 10.1172/JCI172262, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 244.Egbuna O, Zimmerman B, Manos G, Fortier A, Chirieac MC, Dakin LA, et al

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2.3 Impaired alveolar gas-blood barrier In ALI, the alveolar-capillary barriers function is compromised, increasing capillary permeability and protein leakage into alveoli (Esquivel-Ruiz et al., 2021)

S21Cbz-Osu1:0.9-1.1:1-21:1:1.5In an optional embodiment, in S2: the molar ratio of intermediate 1, Cbz-Osu and base is 1:0.9-1.1:1-2, preferably 1:1:1.5