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Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis

Induction of immune tolerance by activation of CD8+ T suppressor/regulatory cells in lupus-prone mice

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Nature 440 , 944948 (2006)

This helps cells regenerate telomeres, which are essential protective parts of our DNA, resulting, among other things, in regulatory abilities of the circadian rhythm and sleep disorders by normalizing melatonin levels, promoting deeper sleep, and strong antioxidant properties