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In this context, it would be interesting to examine the differential ability of different ligands acting on the 2 -AR to recruit -Arr and in turn mediate internalization

However, about 10-15% of acetaminophen is metabolized by CYP2E1 into a toxic metabolite known as NAPQI (N-acetyl-p-benzoquinone imine).[ref] Detoxification with glutathione: NAPQI then needs to be neutralized with glutathione, which is catalyzed using the GST genes