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To learn more about how to address the root causes of intestinal permeability, I encourage you to take a look at my article on gut health

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[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Marchionni S., Sell C., Lorenzini A

Upon cellular stress, characteristic of ASD [158], ROS production and elevated intracellular Ca 2+ concentration trigger mPTP opening leading to mitochondrial membrane permeabilization (MMP) [181], initiating apoptosis and necrosis [269], and regulating the activity of autophagy [270, 271]

Gastroenterology & Hepatology, 17(9), 557588