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The nematode Caenorhabditis elegans (Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y, 1988)

Importantly, this work also revealed impaired synaptic pruning and ASD-like behavioral phenotype in mice lacking neuronal autophagy

indeed, a systematic review and meta-analysis on different supplements containing l-ARG, as single nutraceutical or in combination, reported that only 2% of patients experienced adverse effects when pooling together only supplements containing l-ARG as single nutraceutical

Aging and bone loss Adverse effects of aging are, in part, attributed to decreases in mitochondrial function and increases mitochondrial oxidant production [141]

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This study was supported by the Scientific Research Project Unit of Suleyman Demirel University (project code: TSG-2023-9010)