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The risks of arthritis, advanced liver fibrosis, cirrhosis and the subsequent development of primary liver cancer increase with progressive iron loading, particularly when the serum ferritin level exceeds 1000 mcg/L

Glutathione is often used in therapies aimed at reducing oxidative stress, improving skin health, and boosting overall vitality

However, due to the high overlap of IC/BPS symptoms with other urological conditions, the diagnosis of IC/BPS remains a significant challenge and is usually based on eliminating other disorders

This can be expected to result in GTP depletion

JBC 289, 87358741

PMID 31428651 Bhave S, et al