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Varicocele and the Role of Antioxidants: Varicocele, characterized by the enlargement and dilation of the veins within the scrotum, stands as a prominent correctable factor in male infertility

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Proc Natl Acad Sci USA 1998

A three-year randomized, double-blind, placebo-controlled trial in 818 older adults (aged 50-70 years) with elevated homocysteine levels but normal serum vitamin B 12 levels found that folic acid supplementation (800 g/day) lowered homocysteine levels and improved measures of memory performance (115)