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The metabolites generated during metabolic reprogramming, including lactate and ROS, further impair local mitochondrial function, potentially exacerbating the energy deficit (69) and establishing a potential characteristic metabolic-inflammatory feedback loop in PEM

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It is converted into the androgen dehydroepiandrosterone (DHEA) by the enzyme 17-hydroxylase (CYP17A1)

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GSH ist in Verbindung mit dem Enzym Glutathion-Peroxidase (GP) das aktive Reduktionsmittel, das fr die Minimierung der schdlichen Wasserstoffperoxid-Zellkonzentrationen verantwortlich ist