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Park et al., 2020

Moreover, HMGB1 levels rise in parallel with the severity of the disease, and thus, this protein presents a potential therapeutic target as one of the biomarkers of MASLD [228, 229]

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216 Furthermore, a randomized, double-blind, placebo-controlled trial in 65 hemodialysis patients reported that taking 1,200 mg, but not 600 mg, of CoQ10 daily for four months decreased oxidative stress (as indicated by a decrease in F2-isoprostanes)