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Lan et al., 2023)

Studies indicate that HIF-2, upon stimulation by inflammatory factors such as IL-1, leads to a decrease in GSH levels, thereby increasing chondrocytes sensitivity to lipid peroxidation and ferroptosis

doi: 10.1007/s00125-016-3933-4 33 CintiS

In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target

There are three distinct families of GSTs in mammals: cytosolic, mitochondrial and membrane-associated proteins