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9 Immunosenescence is also regulated by signaling pathways such as the nuclear factor-kappa B (NF-B), mTOR, JAK-STAT, melatonin, and sirtuin pathways, whose dysregulation leads to aberrant immune responses and increased susceptibility to age-related diseases

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This is evidenced by the report that infusion of DCA into rats with severe diabetic ketoacidosis over four hours caused a marked decrease in blood ketone bodies concentration 12, 13

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Wang et al., 2008b)

Based on the stated hypotheses, group differences were examined in each region for GABA, Glu, Gln, Gln/Glu, and Lac with significance set to p 5 years illness duration) illness durations