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The absence of pathognomonic imaging patterns, limited prospective studies, and a need for standardized criteria underscore the challenges in accurately diagnosing and understanding lipedema, necessitating more robust research approaches
doi: 10.3390/molecules27041149 15 ZhaoHZhuWZhaoXLiXZhouZZhengMet al

The MDH2 catalyzes the reversible oxidation of malate to oxaloacetate using NAD+/NADH as a cofactor in the citric acid cycle (45)
10.3109/21678421.2013.824000 [DOI] [PubMed] [Google Scholar] McCampbell A, Cole T, Wegener AJ, Tomassy GS, Setnicka A, Farley BJ, Schoch KM, Hoye ML, Shabsovich M, Sun L, Luo Y, Zhang M, Comfort N, Wang B, Amacker J, Thankamony S, Salzman DW, Cudkowicz M, Graham DL, Miller TM (2018)

Research shows that antibiotics prescribed to humans are used at home and finally end up in the sewage

& Yuste, R