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Tirzepatide, the first dual GIP/GLP-1 receptor agonist (RA), received US Food and Drug Administration (FDA) approval for the treatment of T2DM in May 2022 and for chronic weight management in November 2023 [4]

Most people who supplement intentionally notice subtle shifts over several weeks of consistent use

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For maximum benefit, consider a split dosing protocol: a serving before drinking (ideally 250-500mg, or your supplement's labeled dosage), and another immediately upon waking up the next day

Kurhanewicz, J