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J Cell Commun Signal 5(1):2538

Transgenic expression of SOD1 specifically in neurons of Sod1 deficient mice prevents defects in muscle mitochondrial function and calcium handling

While TNF- is among the most potent activators of NF-B, its own expression is also regulated by NF-B, creating a feedback loop that perpetuates inflammation

doi: 10.1007/s13311-014-0329-3

Sun L, Bckmann RA

The central mechanism responsible for the accurate function of clock genes is based on a transcription/translation negative and positive feedback loop ( The positive branch of rhythmic genes consists of circadian locomotor output cycles kaput (CLOCK) and brain and muscle ARNT-like/basic helixloophelix ARNT-like 1 (BMAL1)