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doi: 10.1016/j.bbadis.2015.08.001 56 OlaMSNawazMIKhanHAAlhomidaAS

Lancet 369 , 19801982 (2007)

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Mechanism of Action ARA-290 has been investigated for its selective activation of the innate repair receptor (IRR), a heterodimeric complex composed of the EPO receptor and beta common receptor (CD131)

Most bioenergy- and NAD + -dependent signaling pathways are activated in different subcellular compartments, and locally accessible NAD + is required for these metabolic processes
