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However, by slightly altering the chemical structure of this nutrient (adding the acetyl group), it can cross the blood-brain barrier and function to support both brain health and energy production

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Intestinal absorption occurs predominantly in the small bowel through active transport systems, specifically mediated by organic cation transporters (OCTN family)

2016;104 Suppl 3(Suppl 3):864S-867S

3.2 Carnitine deficiency across the course of diet therapy Of the 47 patients with a normal free carnitine level at baseline prior to starting MAD, 18 (38.3%) patients developed free carnitine deficiency during the course of diet therapy

This is why some people consider taking carnitine supplements, particularly those looking to enhance their physical performance or who have certain health conditions that might affect carnitine production