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Due to its delocalized positive charge, berberine can disrupt mitochondrial membrane potential and upregulate the content of ROS

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As expected, -tocopherol efficiently inhibited the peroxidation of membrane phospholipids as judged by its effect on the autoxidation of unilammelar liposomes of egg phosphatidylcholine induced by the lipophilic hyponitrite DTUN (di- tert -undecylhyponitrite, (49)

S., Barreira, D

doi: 10.1016/j.neuroscience.2013.03.032

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