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The results from this study provide evidence that supplementary CoQ10 can provide further pain relief in FM patients treated with pregabalin, through reducing oxidative stress imbalance and inflammation and improving mitochondrial function

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In the FRDA-lymphoblast cell line, treatment with DMF shows increased transcription initiation and procession following GAA expansion tracts, as well as increased mtDNA copy number (Jasoliya et al., 2019)