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The combination of inosine with anti-CTLA4 and anti-PD1 antibodies significantly reduced tumor growth in B16-GMCSF mouse models [81]

In Northern China, the prevalence is 20%, while, in Mexico, it could be as high as 32% [99]

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Peroxynitrite is believed to inhibit electron flow at CI, CIII, and minimally at CIV via direct interaction with the complexes (Poderoso et al., 2019)
