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This enzyme is mostly located in the cellular compartments of high electron flux, i.e

It stimulates the production of several downstream antioxidants, anti-inflammatory proteins, and detoxification enzymes by triggering the Kelch-like ECH-associating protein 1 (Keap1)-Nrf2-antioxidant response element (ARE) signaling pathway

TST expression profiles in human diseases with mitochondrial dysfunction Publicly available RNA sequencing and proteomic databases, including the GTEx project and the Human Protein Atlas (HPA) [115,116], reveal that TST is highly expressed in many organs with high metabolic activity such as liver, colon, kidney and brain

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doi: 10.1007/s00109-023-02407-3 77 FujitaK.YamauchiM.ShibayamaK.AndoM.HondaM.NagataY

Interactions Does glutathione interact with foods or drinks