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Different crystallization pathways have been described in bile supersaturated with cholesterol

BMJ Glob Health 6:e003176

FF (500 L) was mixed with methanol-acetonitrile (400 L, v/v = 2:1, with formic acid and succinic acid-2,2,3,3-d4), and KGN cells (110 7 ) were treated with methanol-water (v/v = 3:1, with 0.1% formic acid and succinic acid-2,2,3,3-d4), respectively

Krummel, M

Proceedings of the National Academy of Sciences of the United States of America 115: 10836-10844