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skin flushing is far less common with nicotinamide than with niacin (nicotinic acid)

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The peptide also showed no significant effects on blood pressure, heart rate, or other cardiovascular parameters

Zenobi PD, Graf S, Ursprung H, Froesch ER

A separate 2024 meta-analysis (Alshammari et al.) confirmed the same conclusion, further strengthening the evidence base
