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Moreover, these data provide a metabolic avenue for inducing HR deficiency and promoting sensitivity to DNA-damaging agents

Some American Cocker Spaniels have been reported to develop DCM associated with low taurine levels

Nitrogen scavengers drugs are key drugs in hyperammonemia caused by inborn errors of metabolism and can help to reduce the ammonia plasma level in ALF (Figure 3)

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Similarly, the higher acetylcarnitine dose (1.5 g) increased plasma carnitine from 35.3 M (IQR: 25.748.0) at baseline to 43.9 M (IQR: 35.847.9) at 16 h, an effect comparable to that of 0.5 g of carnitine