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Description
Major contributors to ROS production include mitochondrial dysfunction, cytochrome P450 2E1 (CYP2E1), and NADPH oxidase (NOX) enzymes
The main pathological manifestation of PD is the huge loss of dopaminergic neurons owing to the accumulation of reactive oxygen species (ROS) and the abnormal aggregation of the -synuclein (-syn) protein
Targets: Bonded GHK amino acid strands and copper ions are common and beneficial to the human body
doi: 10.7150/ijbs.41051 102 LiXGracillaDCaiLZhangMYuXChenXet al
Zhu et al., 2022b) with minimal compromise of viability (Zhu et al., 2021), evidencing a decrease in mitochondrial ROS levels (Zhu et al., 2021
However, recent results confirmed that glutamate, acetylcholine, serotonin, and GABA changes may also contribute to the pathology of the diseases
