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doi: 10.1002/1097-0142(19840915)54:6 3.0.co;2-1

LRRK2 p.G2019S disrupts mitochondrial mitophagy by impairing the MiroPINK1/PARKIN pathway, hence hindering cellular respiration and metabolism (158)

Similar to potassium intake, calcium levels are harder to regulate when the kidneys malfunction

Sumoylation in Physiology, Pathology and Therapy

It preserves cardiac sarcoplasmic reticulum Ca 2+ -ATPase and hexokinase type I during myocardial infarction, exhibiting cardioprotective activity effects by activating NO synthetase, which stimulates the synthesis of GBB [25, 58]

Role of L-Arginine in Nitric Oxide Synthesis and Health in Humans 2
