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3 Results 3.1 Increased glucose tolerance and cold sensitivity upon gut microbiota-depletion is independent of UCP1 + cells To study the contribution of brown and beige adipocytes to enhanced glucose tolerance upon gut microbiota deletion, we used the Ucp1Dtr2Gfp mouse line (Ucp1DTR), which allows for transient ablation of UCP1 + cells upon diphtheria toxin (DT) injections as described previously ( Figure 1A )

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doi: 10.1515/reveh-2015-0026

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