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I've put together a full literature review, all the key papers, mechanism data, TGA and FDA regulatory status, and safety profile

Among the reasons B12 may not get absorbed into the body are the following: Some people dont absorb B12 because their stomachs dont make the needed protein

doi: 10.1159/000093982

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it is the physical-chemistry context that explains the dosing schedules seen in the trials

The firm acknowledged that releasing OOS compounded preparations reflects a deviation from internal quality assurance procedures and obligation to notify patients and prescribers. But the FDA found that no corrective actions were provided to address the failure to notify patients and prescribers when OOS results were identified