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Cellular damage in DILI can reflect toxic effects of the culprit medication or its metabolites, or immune-mediated effects (Figure 1)

AMA, American Medical Association

Food and Drug Administration approval of Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc) injection for subcutaneous use in generalized myasthenia gravis

S-(1,2,2-trichlorovinyl)-L-cysteine sulfoxide, a reactive metabolite of S-(1,2,2-Trichlorovinyl)-L-cysteine formed in rat liver and kidney microsomes, is a potent nephrotoxicant

RAKIETEN, N., GORDON, B.S., COONEY, D.A., DAVIS, R.D., & SCHEIN, P.S

The molecular weight of 4,114 Daltons makes milk transfer unlikely
