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Not for human dosing, ingestion, injection, or administration

European journal of nutrition , 54 (2), 251263

Commercial GHK-Cu serums typically claim 6-12 month shelf life unopened when properly formulated with preservatives and appropriate pH, dropping to 3-6 months after opening due to air exposure and contamination introduction
It is localized to the mitochondria and showed non-substrate behavior for major CYP450 isoforms (2C9, 2D6, 3A4), along with no inhibitory effects against CYP1A2, 2C9, 2D6, 2C19, and 3A4, suggesting a low risk of metabolic interactions

Circulation (2005) 112(19):29933000

Hand therapy is recommended to prevent soft-tissue atrophy and joint contracture (typically extension of MCP joint and flexion of PIP joint), which leads to a poor outcome, and subsequent treatment is difficult
